Calcium α-Ketoglutarate (Ca-AKG)

Calcium α-Ketoglutarate (Ca-AKG) serves as a unique dietary supplement due to its dual benefits derived from calcium and 2-oxoglutarate. 

Products Description

In the realm of nutritional supplements, Calcium α-Ketoglutarate (Ca-AKG) stands out as a compound with multifaceted benefits, offering a blend of calcium and 2-oxoglutarate that holds promise in various aspects of health and wellness.

α-Ketoglutaric acid (AKG) is a naturally occurring compound in the human body that is involved in the Krebs cycle (or citric acid cycle), a key part of cellular energy production. It serves as an intermediate that helps in the conversion of nutrients into usable energy (ATP). AKG also plays a role in amino acid metabolism and acts as a precursor for the synthesis of glutamine and other amino acids.

Ca-AKG is formed by binding α-ketoglutaric acid to calcium, which enhances the compound’s stability and absorption when taken as a supplement. This combination provides the benefits of both calcium (an essential mineral for bone health and cellular function) and AKG.


Chemical Properties and Synthesis:


Calcium α-Ketoglutarate (Ca-AKG), chemically represented as Ca(C5H4O5)2, is a calcium salt of 2-oxoglutaric acid, also known as alpha-ketoglutaric acid. This compound is characterized by its white crystalline appearance and solubility in water. Its chemical structure comprises calcium ions (Ca^2+) bound to two molecules of 2-oxoglutarate, forming a stable complex. Synthesizing Calcium α-Ketoglutarate (Ca-AKG) typically involves the reaction between calcium carbonate or calcium hydroxide with 2-oxoglutaric acid under controlled conditions. The resulting product is then purified to obtain the desired compound with high efficacy and purity levels.


Potential Health Benefits of Ca-AKG


Supports Cellular Energy Production:

Ca-AKG contributes to the efficient production of ATP, which is critical for energy metabolism in cells. This can help improve energy levels and reduce fatigue.

Promotes Longevity and Anti-Aging:

Research has indicated that AKG may have anti-aging effects by supporting cellular health and preventing age-related cellular decline. It has been studied for its role in reducing oxidative stress and promoting mitochondrial function.

Enhances Bone Health:

The calcium component of Ca-AKG contributes to bone density and strength, making it beneficial for overall bone health.

Aids in Muscle Recovery and Performance:

Athletes and those engaged in intense physical activity may benefit from Ca-AKG for its potential to support protein synthesis and recovery after exercise.

Supports Metabolic Health:

AKG’s role in the Krebs cycle helps maintain a healthy metabolism and efficient nutrient processing.

Detoxification:

Ca-AKG is involved in amino acid metabolism and may help in the detoxification process by supporting the removal of ammonia and other nitrogenous waste products from the body.


Functions and Usages:


Calcium α-Ketoglutarate (Ca-AKG) serves as a unique dietary supplement due to its dual benefits derived from calcium and 2-oxoglutarate. Calcium, a vital mineral renowned for its role in bone health, muscle function, and nerve transmission, is effectively delivered through this compound. Additionally, 2-oxoglutarate, an intermediate in the Krebs cycle, contributes to cellular energy production and plays a crucial role in amino acid metabolism. The combination of calcium and 2-oxoglutarate offers synergistic effects, enhancing the absorption and utilization of calcium while supporting metabolic processes within the body. As such, Calcium α-Ketoglutarate (Ca-AKG) finds applications in various dietary supplements aimed at promoting bone health, muscle function, and overall vitality.


Market Information and Outlook:


The market for Calcium α-Ketoglutarate (Ca-AKG) is witnessing steady growth, fueled by increasing consumer awareness regarding the importance of calcium supplementation and the emerging trend of holistic health approaches. With a growing aging population worldwide, there is a rising demand for supplements that support bone density and musculoskeletal health. Calcium α-Ketoglutarate (Ca-AKG), with its unique formulation combining calcium and 2-oxoglutarate, has garnered attention as a promising solution to address these needs. Furthermore, its potential benefits extend beyond bone health, encompassing aspects such as athletic performance, metabolic support, and overall wellness enhancement.


Looking ahead, the market outlook for Calcium α-Ketoglutarate (Ca-AKG) appears favorable, driven by ongoing research efforts aimed at uncovering its full range of therapeutic properties and expanding its applications in dietary supplements and functional foods. Moreover, advancements in synthesis methods and formulation technologies are poised to enhance the efficacy and bioavailability of Calcium α-Ketoglutarate (Ca-AKG)-based products, further bolstering its market presence. As consumer preferences continue to evolve towards preventive healthcare and natural alternatives, Calcium α-Ketoglutarate (Ca-AKG) stands poised to emerge as a key player in the landscape of nutritional supplements, offering a potent blend of calcium and metabolic support for optimal health and vitality.


Calcium α-Ketoglutarate (Ca-AKG) is a promising supplement for those looking to support energy production, promote longevity, and improve metabolic and bone health. Its dual benefit of supplying calcium and AKG makes it a valuable addition to wellness routines aimed at enhancing cellular function and overall vitality.

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